Hs06452962_cn

• Gene Symbol: SERPINB12
• Assay Reference Genome Location: Chr.18:63549849 on build GRCh38
• Cytoband: 18q21.33

Target Gene Details

• Entrez Gene ID: 89777
• Gene Name: serpin family B member 12
• Gene Aliases: YUKOPIN
• Location: Chr.18:63519164-63569329 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINB12	XM_005266778.3			XP_005266835.2
	XM_011526246.1			XP_011524548.1
	XM_011526248.1			XP_011524550.1
	XM_011526249.1			XP_011524551.1
	XM_017026067.1			XP_016881556.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1066552	Chr.18:63147299 - 64608176 on Build GRCh38	Gain	SERPINB11 SERPINB12 SERPINB7 SERPINB5 SERPINB2 SERPINB13 SERPINB3 LOC284294 SERPINB4 LINC00305 SERPINB10 SERPINB8 VPS4B BCL2 HMSD KDSR LINC01538
esv3642772	Chr.18:63548916 - 63550153 on Build GRCh38	Loss	SERPINB12

More Information

Additional Information:

For this assay, SNP(s) [rs74528146] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

hematopoietic progenitor cell differentiation
negative regulation of endopeptidase activity
negative regulation of protein catabolic process

Function(s)

serine-type endopeptidase inhibitor activity
enzyme binding