Hs06457119_cn

• Gene Symbol: POLI
• Assay Reference Genome Location: Chr.18:54291103 on build GRCh38
• Cytoband: 18q21.2

Target Gene Details

• Entrez Gene ID: 11201
• Gene Name: DNA polymerase iota
• Gene Aliases: RAD30B, RAD3OB
• Location: Chr.18:54269479-54321266 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLI	NM_007195.2			NP_009126.2
	XM_005258188.3			XP_005258245.1
	XM_005258192.4			XP_005258249.1
	XM_006722378.2			XP_006722441.1
	XM_011525796.2			XP_011524098.1
	XM_011525797.1			XP_011524099.1
	AF140501.1			AAD50381.1
	AF245438.1			AAF63383.1
	AK226057.1
	AK301578.1
	AL136670.1			CAB66605.1
	BC032662.1			AAH32662.1
	BX649100.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv433313	Chr.18:54278760 - 54293665 on Build GRCh38	Loss	POLI

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication
DNA repair
translesion synthesis
error-prone translesion synthesis

Function(s)

damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
metal ion binding