Hs06482072_cn

• Gene Symbol: RBBP8
• Assay Reference Genome Location: Chr.18:22917579 on build GRCh38
• Cytoband: 18q11.2

Target Gene Details

• Entrez Gene ID: 5932
• Gene Name: RB binding protein 8, endonuclease
• Gene Aliases: COM1, CTIP, JWDS, RIM, SAE2, SCKL2
• Location: Chr.18:22914121-23026486 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RBBP8	XM_006722519.2			XP_006722582.1
	XM_006722520.2			XP_006722583.1
	XM_011526132.2			XP_011524434.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2227	Chr.18:22900840 - 22927879 on Build GRCh38	Insertion	RBBP8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

cell cycle checkpoint
G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
blastocyst hatching
DNA replication
DNA repair
nucleotide-excision repair
regulation of transcription from RNA polymerase II promoter
mitotic nuclear division
DNA double-strand break processing involved in repair via single-strand annealing
G2 DNA damage checkpoint
response to estradiol
cell division
meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator

Function(s)

single-stranded DNA endodeoxyribonuclease activity
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription corepressor activity
damaged DNA binding
protein binding