Hs06643595_cn

• Gene Symbol: CD80
• Assay Reference Genome Location: Chr.3:119528429 on build GRCh38
• Cytoband: 3q13.33

Target Gene Details

• Entrez Gene ID: 941
• Gene Name: CD80 molecule
• Gene Aliases: B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
• Location: Chr.3:119523909-119559709 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD80	NM_005191.3			NP_005182.1
	XM_011513327.2			XP_011511629.1
	AK292129.1
	AY197777.1			AAO39208.1
	AY197778.1			AAO39209.1
	BC042665.1			AAH42665.1
	M27533.1			AAA36045.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829695	Chr.3:119460043 - 119649149 on Build GRCh38	Loss	POPDC2 TMEM39A POGLUT1 PLA1A CD80 ADPRH TIMMDC1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

cell-cell signaling
positive regulation of signal transduction
regulation of phosphatidylinositol 3-kinase signaling
T cell costimulation
intracellular signal transduction
T cell activation
positive regulation of interleukin-2 biosynthetic process
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
positive regulation of T-helper 1 cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of alpha-beta T cell proliferation
viral entry into host cell
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of peptidyl-tyrosine phosphorylation
cellular response to lipopolysaccharide

Function(s)

virus receptor activity
protein binding
coreceptor activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity