Hs06746055_cn

• Gene Symbol: TRMT11
• Assay Reference Genome Location: Chr.6:126000212 on build GRCh38
• Cytoband: 6q22.32

Target Gene Details

• Entrez Gene ID: 60487
• Gene Name: tRNA methyltransferase 11 homolog
• Gene Aliases: C6orf75, MDS024, TRM11, TRMT11-1
• Location: Chr.6:125986430-126083131 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT11	NM_001031712.2			NP_001026882.2
	XM_017011168.1			XP_016866657.1
	XM_017011169.1			XP_016866658.1
	AF182423.1			AAG14959.1
	AF532977.1			AAQ10284.1
	AK308651.1
	BC056878.1			AAH56878.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1025069	Chr.6:125973448 - 126003809 on Build GRCh38	Loss	HINT3 TRMT11
nsv1022677	Chr.6:125935606 - 126195159 on Build GRCh38	Gain	HINT3 TRMT11
nsv1019490	Chr.6:125927450 - 126221150 on Build GRCh38	Loss	HINT3 NCOA7 TRMT11
nsv830796	Chr.6:125844487 - 126015022 on Build GRCh38	Loss	HINT3 NCOA7 TRMT11

More Information

Additional Information:

For this assay, SNP(s) [rs116438177] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

tRNA methylation

Function(s)

tRNA binding
tRNA (guanine-N2-)-methyltransferase activity