Hs06943173_cn

• Gene Symbol: KRT18
• Assay Reference Genome Location: Chr.12:52950666 on build GRCh38
• Cytoband: 12q13.13

Target Gene Details

• Entrez Gene ID: 3875
• Gene Name: keratin 18
• Gene Aliases: CK-18, CYK18, K18
• Location: Chr.12:52948871-52952901 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KRT18	NM_000224.2			NP_000215.1
	NM_199187.1			NP_954657.1
	AK129587.1
	AK223093.1			BAD96813.1
	AK308506.1
	AK313988.1
	AY762101.1			AAX07828.1
	BC000180.2			AAH00180.1
	BC000698.2			AAH00698.1
	BC004253.1			AAH04253.1
	BC008636.1			AAH08636.1
	BC020982.1			AAH20982.1
	BC072017.1			AAH72017.1
	BG753529.1
	BT019412.1			AAV38219.1
	CD106591.1
	X12881.1			CAA31375.1
	X12883.1			CAA31377.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832416	Chr.12:52779656 - 52971582 on Build GRCh38	Loss	KRT8 KRT79 KRT78 KRT4 KRT18 KRT3
nsv973068	Chr.12:52950527 - 52952866 on Build GRCh38	Duplication	KRT18

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cell cycle
anatomical structure morphogenesis
viral process
tumor necrosis factor-mediated signaling pathway
Golgi to plasma membrane CFTR protein transport
negative regulation of apoptotic process
intermediate filament cytoskeleton organization
extrinsic apoptotic signaling pathway
hepatocyte apoptotic process
cell-cell adhesion

Function(s)

structural molecule activity
protein binding
poly(A) RNA binding
scaffold protein binding
cadherin binding involved in cell-cell adhesion