Hs06943962_cn

• Gene Symbol: MAP3K12
• Assay Reference Genome Location: Chr.12:53493973 on build GRCh38
• Cytoband: 12q13.13

Target Gene Details

• Entrez Gene ID: 7786
• Gene Name: mitogen-activated protein kinase kinase kinase 12
• Gene Aliases: DLK, MEKK12, MUK, ZPK, ZPKP1
• Location: Chr.12:53480492-53501066 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP3K12	NM_001193511.1			NP_001180440.1
	NM_006301.3			NP_006292.3
	XM_005269140.2			XP_005269197.1
	XM_011538725.2			XP_011537027.1
	AK094195.1
	BC050050.1			AAH50050.1
	U07358.1			AAA67343.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
JNK cascade
histone phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
intracellular signal transduction
protein autophosphorylation
mitophagy in response to mitochondrial depolarization
negative regulation of motor neuron apoptotic process

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
protein homodimerization activity