Hs06969078_cn

• Gene Symbol: SCYL2
• Assay Reference Genome Location: Chr.12:100271718 on build GRCh38
• Cytoband: 12q23.1

Target Gene Details

• Entrez Gene ID: 55681
• Gene Name: SCY1 like pseudokinase 2
• Gene Aliases: CVAK104
• Location: Chr.12:100267137-100341724 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCYL2	NM_001317784.1			NP_001304713.1
	NM_017988.5			NP_060458.3
	XM_017019618.1			XP_016875107.1
	XM_017019619.1			XP_016875108.1
	XM_017019620.1			XP_016875109.1
	AK000936.1			BAA91433.1
	AK125091.1
	AK292980.1
	BC063798.1			AAH63798.1
	DA234206.1
	DB127407.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv559964	Chr.12:99872025 - 100538490 on Build GRCh38	Gain	SCYL2 DEPDC4 SLC17A8 UHRF1BP1L MIR1827 ACTR6 ANKS1B NR1H4 GOLGA2P5

More Information

Additional Information:

For this assay, SNP(s) [rs144836561] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of receptor internalization
protein phosphorylation
endosome to lysosome transport
negative regulation of canonical Wnt signaling pathway
receptor internalization involved in canonical Wnt signaling pathway
positive regulation of clathrin-mediated endocytosis

Function(s)

protein kinase activity
receptor binding
protein binding
ATP binding