Hs06985446_cn

• Gene Symbol: DTX1
• Assay Reference Genome Location: Chr.12:113071116 on build GRCh38
• Cytoband: 12q24.13

Target Gene Details

• Entrez Gene ID: 1840
• Gene Name: deltex E3 ubiquitin ligase 1
• Gene Aliases: hDx-1
• Location: Chr.12:113056711-113098028 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DTX1	NM_004416.2			NP_004407.2
	XM_011538009.2			XP_011536311.1
	AF053700.1			AAC06246.1
	BC048216.1			AAH48216.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv519540	Chr.12:113042705 - 113459599 on Build GRCh38	Gain+Loss	IQCD MIR6762 PLBD2 MIR7106 TPCN1 SDS SLC8B1 RASAL1 DDX54 RITA1 CFAP73 DTX1 SDSL
nsv560264	Chr.12:113050137 - 113136469 on Build GRCh38	Loss	RASAL1 DTX1
esv3630792	Chr.12:112988703 - 113838810 on Build GRCh38	Gain	LINC01234 IQCD MIR6762 PLBD2 MIR7106 TPCN1 LHX5-AS1 SDS RBM19 SLC8B1 RASAL1 OAS2 DDX54 RITA1 CFAP73 DTX1 LHX5 SDSL

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
transcription from RNA polymerase II promoter
cell surface receptor signaling pathway
Notch signaling pathway
regulation of Notch signaling pathway
glial cell differentiation
protein ubiquitination
negative regulation of T cell differentiation
negative regulation of neuron differentiation
regulation of nucleic acid-templated transcription

Function(s)

transcription coactivator activity
Notch binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
ubiquitin protein ligase binding