Hs07013606_cn

• Gene Symbol: P3H3
• Assay Reference Genome Location: Chr.12:6836527 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10536
• Gene Name: prolyl 3-hydroxylase 3
• Gene Aliases: GRCB, HSU47926, LEPREL2
• Location: Chr.12:6828373-6839854 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
P3H3	NM_014262.4			NP_055077.2
	AB209320.1			BAD92557.1
	AJ430349.1			CAD23037.1
	AK025976.1
	AK126766.1
	AK297917.1
	BC017217.2			AAH17217.2
	BC067251.1			AAH67251.1
	BC080630.1			AAH80630.1
	U47926.1			AAC50464.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832324	Chr.12:6780297 - 6932306 on Build GRCh38	Loss	SPSB2 TPI1 RPL13P5 ATN1 GPR162 CD4 LRRC23 LOC105369632 ENO2 USP5 CDCA3 DSTNP2 P3H3 GNB3
esv3580405	Chr.12:6826466 - 6903969 on Build GRCh38	Gain	SPSB2 LOC105369632 USP5 TPI1 CDCA3 RPL13P5 DSTNP2 GPR162 P3H3 GNB3
nsv832323	Chr.12:6662233 - 6856559 on Build GRCh38	Loss	ING4 MLF2 GPR162 CD4 ZNF384 PTMS COPS7A USP5 CDCA3 PIANP P3H3 LAG3 GNB3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

negative regulation of cell proliferation
peptidyl-proline hydroxylation
oxidation-reduction process

Function(s)

iron ion binding
procollagen-proline 3-dioxygenase activity
L-ascorbic acid binding