Hs07019641_cn

• Gene Symbol: KRT8
• Assay Reference Genome Location: Chr.12:52904082 on build GRCh38
• Cytoband: 12q13.13

Target Gene Details

• Entrez Gene ID: 3856
• Gene Name: keratin 8
• Gene Aliases: CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
• Location: Chr.12:52897187-52949866 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KRT8	NM_001256282.1			NP_001243211.1
	NM_001256293.1			NP_001243222.1
	NM_002273.3			NP_002264.1
	NR_045962.1
	AK222941.1			BAD96661.1
	AK290938.1
	AK310257.1
	AK315826.1
	BC000654.2
	BC008200.1			AAH08200.1
	BC063513.1
	BC073760.1			AAH73760.1
	BC075839.1			AAH75839.1
	BX417476.2
	DA825311.1
	M26512.1			AAA51542.1
	M34225.1			AAA35748.1
	M77025.1
	U76549.1			AAB18966.1
	X74929.1			CAA52882.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv558965	Chr.12:52862019 - 52913242 on Build GRCh38	Loss	KRT8
nsv832416	Chr.12:52779656 - 52971582 on Build GRCh38	Loss	KRT18 KRT78 KRT79 KRT4 KRT3 KRT8
esv3581638	Chr.12:52883196 - 52908855 on Build GRCh38	Gain	KRT8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

viral process
tumor necrosis factor-mediated signaling pathway
sarcomere organization
response to hydrostatic pressure
response to other organism
cell differentiation involved in embryonic placenta development
extrinsic apoptotic signaling pathway
hepatocyte apoptotic process

Function(s)

structural molecule activity
protein binding
protein complex binding
scaffold protein binding