Hs07067447_cn

• Gene Symbol: PRKCH
• Assay Reference Genome Location: Chr.14:61288648 on build GRCh38
• Cytoband: 14q23.1

Target Gene Details

• Entrez Gene ID: 5583
• Gene Name: protein kinase C eta
• Gene Aliases: PKC-L, PKCL, PRKCL, nPKC-eta
• Location: Chr.14:61280953-61550980 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRKCH	XM_017021458.1			XP_016876947.1
	AK296158.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv564881	Chr.14:60457291 - 61377535 on Build GRCh38	Gain	LOC105378189 C14orf39 PRKCH MNAT1 SLC38A6 TRMT5 SALRNA1 TMEM30B SIX4 SIX6 SIX1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
signal transduction
positive regulation of macrophage derived foam cell differentiation
peptidyl-serine phosphorylation
platelet activation
negative regulation of glial cell apoptotic process
intracellular signal transduction
positive regulation of keratinocyte differentiation
positive regulation of B cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
positive regulation of glial cell proliferation
protein kinase C signaling
regulation of bicellular tight junction assembly

Function(s)

protein kinase C activity
calcium-independent protein kinase C activity
ATP binding
Ral GTPase binding
enzyme binding
metal ion binding