Hs07096241_cn

• Gene Symbol: DIO2
• Assay Reference Genome Location: Chr.14:80219191 on build GRCh38
• Cytoband: 14q31.1

Target Gene Details

• Entrez Gene ID: 1734
• Gene Name: deiodinase, iodothyronine, type II
• Gene Aliases: 5DII, D2, DIOII, SelY, TXDI2
• Location: Chr.14:80197525-80231054 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DIO2	NM_000793.5			NP_000784.2
	AK292210.1

Target Gene Details

• Entrez Gene ID: 100628307
• Gene Name: DIO2 antisense RNA 1
• Gene Aliases: -
• Location: Chr.14:80211419-80455467 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DIO2-AS1	NR_038355.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1045241	Chr.14:79419018 - 80267858 on Build GRCh38	Gain	NRXN3 DIO2-AS1 DIO2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

selenocysteine incorporation
thyroid hormone generation
thyroid hormone metabolic process
hormone biosynthetic process
oxidation-reduction process

Function(s)

thyroxine 5'-deiodinase activity
selenium binding
ubiquitin protein ligase binding