Hs07129691_cn

• Gene Symbol: CYP4F11
• Assay Reference Genome Location: Chr.19:15921171 on build GRCh38
• Cytoband: 19p13.12

Target Gene Details

• Entrez Gene ID: 57834
• Gene Name: cytochrome P450 family 4 subfamily F member 11
• Gene Aliases: CYPIVF11
• Location: Chr.19:15912370-15934866 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP4F11	NM_001128932.1			NP_001122404.1
	NM_021187.3			NP_067010.3
	AF236085.1			AAG15889.1
	AK125714.1
	AK289424.1
	AL833940.1			CAD38795.2
	BC016853.1			AAH16853.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2671181	Chr.19:15768634 - 15926128 on Build GRCh38	Deletion	CYP4F2 LOC102724279 OR10H5 OR10H1 CYP4F24P UCA1 CYP4F11
esv3334671	Chr.19:15673766 - 15931354 on Build GRCh38	Duplication	CYP4F12 CYP4F2 LOC102724279 OR10H5 OR10H3 OR10H1 CYP4F24P OR10H2 UCA1 CYP4F11
nsv833766	Chr.19:15759095 - 15956904 on Build GRCh38	Loss	CYP4F2 LOC102724279 OR10H5 OR10H1 CYP4F24P UCA1 OR10H4 CYP4F11
nsv1064684	Chr.19:15311319 - 16062011 on Build GRCh38	Gain	CYP4F2 BRD4 CYP4F22 OR10H3 CYP4F24P CYP4F3 WIZ PGLYRP2 UCA1 OR10H4 CYP4F11 AKAP8 LINC00661 CYP4F12 LOC102724279 OR10H5 MIR1470 OR10H1 OR10H2 CYP4F8 AKAP8L LINC00905 RASAL3
esv2718244	Chr.19:15743561 - 15951200 on Build GRCh38	Deletion	CYP4F2 LOC102724279 OR10H5 OR10H1 CYP4F24P UCA1 OR10H4 CYP4F11

More Information

Additional Information:

For this assay, SNP(s) [rs74957415] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

inflammatory response
blood coagulation
menaquinone catabolic process
phylloquinone catabolic process
vitamin K catabolic process
oxidation-reduction process

Function(s)

monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
heme binding