Hs07159642_cn

• Gene Symbol: IFNL1
• Assay Reference Genome Location: Chr.19:39297773 on build GRCh38
• Cytoband: 19q13.2

Target Gene Details

• Entrez Gene ID: 282618
• Gene Name: interferon lambda 1
• Gene Aliases: IL-29, IL29
• Location: Chr.19:39296325-39298672 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IFNL1	NM_172140.1			NP_742152.1
	AY129150.1			AAN28265.1
	AY184372.1			AAN86125.1
	AY336716.1			AAR24511.1
	BC074985.2			AAH74985.1
	BC117482.1
	BC126183.1
	HQ214053.1
	JF268782.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833830	Chr.19:39218898 - 39347206 on Build GRCh38	Loss	LRFN1 IFNL3 IFNL1 IFNL2 GMFG SAMD4B IFNL4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

interleukin superfamily

Gene Ontology Categories:

Process(es)

negative regulation of type 2 immune response
JAK-STAT cascade
negative regulation of cell proliferation
negative regulation of interleukin-13 production
negative regulation of interleukin-5 production
positive regulation of interferon-gamma production
positive regulation of tyrosine phosphorylation of STAT protein
negative regulation of memory T cell differentiation
innate immune response
positive regulation of MHC class I biosynthetic process
negative regulation of T cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of JAK-STAT cascade
positive regulation of immune response
defense response to virus

Function(s)

receptor binding
cytokine activity
interleukin-28 receptor binding