Hs07162995_cn

• Gene Symbol: ACOT8
• Assay Reference Genome Location: Chr.20:45853733 on build GRCh38
• Cytoband: 20q13.12

Target Gene Details

• Entrez Gene ID: 10005
• Gene Name: acyl-CoA thioesterase 8
• Gene Aliases: HNAACTE, NAP1, PTE-1, PTE-2, PTE1, PTE2, hACTE-III, hTE
• Location: Chr.20:45841721-45857409 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ACOT8	NM_005469.3			NP_005460.2
	XM_005260239.3			XP_005260296.1
	XM_011528480.2			XP_011526782.1
	AF014404.1			AAB71665.1
	AF124264.1			AAD27616.1
	AK056668.1
	AK292494.1
	AK296973.1
	AK298783.1
	BC117155.1
	BC117157.1
	BI911038.1
	CR541771.1			CAG46570.1
	CR541778.1			CAG46577.1
	DB470803.3
	X86032.1			CAA60024.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv458993	Chr.20:45842587 - 45880235 on Build GRCh38	Loss	ZSWIM3 ACOT8 SNX21
nsv833990	Chr.20:45771510 - 45946844 on Build GRCh38	Loss	ZSWIM3 SPATA25 TNNC2 WFDC3 PCIF1 ACOT8 DNTTIP1 LOC107985388 SNX21 PLTP ZSWIM1 UBE2C NEURL2 CTSA

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

esterase

Gene Ontology Categories:

Process(es)

acyl-CoA metabolic process
bile acid biosynthetic process
viral process
peroxisome fission
fatty acid beta-oxidation using acyl-CoA oxidase
long-chain fatty-acyl-CoA biosynthetic process
alpha-linolenic acid metabolic process
dicarboxylic acid catabolic process
negative regulation of CD4 biosynthetic process

Function(s)

acetyl-CoA hydrolase activity
receptor binding
protein binding
CoA hydrolase activity
palmitoyl-CoA hydrolase activity
choloyl-CoA hydrolase activity
acyl-CoA hydrolase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity