Hs07190238_cn

• Gene Symbol: DSTN
• Assay Reference Genome Location: Chr.20:17569861 on build GRCh38
• Cytoband: 20p12.1

Target Gene Details

• Entrez Gene ID: 11034
• Gene Name: destrin, actin depolymerizing factor
• Gene Aliases: ACTDP, ADF, HEL32, bA462D18.2
• Location: Chr.20:17569173-17608242 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DSTN	XM_011529142.1			XP_011527444.1
	XM_011529143.1			XP_011527445.1
	XM_011529144.1			XP_011527446.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3645426	Chr.20:17565932 - 17576804 on Build GRCh38	Gain	DSTN BFSP1
nsv510781	Chr.20:17543816 - 17598731 on Build GRCh38	Deletion	DSTN BFSP1
nsv520496	Chr.20:17556667 - 17577072 on Build GRCh38	Gain	DSTN BFSP1

More Information

Additional Information:

For this assay, SNP(s) [rs113114461] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

actin polymerization or depolymerization
actin filament depolymerization
positive regulation of actin filament depolymerization
actin filament severing

Function(s)

protein binding
actin filament binding