Hs07495600_cn

• Gene Symbol: RAB40B
• Assay Reference Genome Location: Chr.17:82675911 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 10966
• Gene Name: RAB40B, member RAS oncogene family
• Gene Aliases: RAR, SEC4L
• Location: Chr.17:82657067-82698722 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RAB40B	NM_006822.2			NP_006813.1
	XM_005256334.4			XP_005256391.1
	XM_005256335.3			XP_005256392.1
	XM_017024042.1			XP_016879531.1
	AB209711.1			BAD92948.1
	AL047483.1
	BC018039.1			AAH18039.1
	U05227.1			AAA17031.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	WDR45B FN3KRP RAB40B TBCD B3GNTL1 LOC105371944 FN3K METRNL LOC105376791 FOXK2 LOC101929552 MIR4525 ZNF750
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	FN3KRP FN3K RAB40B LOC105376791 TBCD LOC101929552 MIR4525 ZNF750
nsv952395	Chr.17:82663725 - 82745024 on Build GRCh38	Deletion	FN3KRP FN3K RAB40B LOC105376791 LOC101929552 MIR4525
nsv1067362	Chr.17:82569201 - 82681793 on Build GRCh38	Gain	WDR45B RAB40B FOXK2 MIR4525
nsv1062980	Chr.17:82408938 - 82687942 on Build GRCh38	Gain	OGFOD3 NARF WDR45B C17orf62 HEXDC RAB40B FOXK2 MIR4525
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	AATK-AS1 FN3KRP CCDC57 NOTUM ANAPC11 PDE6G FAAP100 LRRC45 MIR4740 PCYT2 ACTG1 MRPL12 BAHCC1 HGS SIRT7 LOC101929552 ZNF750 PYCR1 LOC100130370 TBCD NARF P4HB SLC25A10 C17orf62 B3GNTL1 TMEM105 MIR6787 HEXDC ARHGDIA LOC105376791 FOXK2 MAFG SLC38A10 STRA13 WDR45B NPLOC4 DCXR MYADML2 MIR3186 LOC105376790 GPS1 NPB PPP1R27 RFNG MAFG-AS1 ALYREF TEPSIN ARL16 MIR6786 ASPSCR1 FN3K MCRIP1 FSCN2 AATK CCDC137 MIR4525 C17orf89 FASN SNORD134 LOC101929511 DUS1L RAC3 RAB40B OXLD1 GCGR OGFOD3 SLC16A3 CD7 LINC00482 LOC105371944 CSNK1D CEP131 SECTM1 UTS2R LOC105371925 TEX19 TSPAN10
nsv509680	Chr.17:82661313 - 82679596 on Build GRCh38	Insertion	RAB40B MIR4525
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	WDR45B FN3KRP LOC105376790 LOC101929511 RAB40B TBCD OGFOD3 NARF CD7 C17orf62 HEXDC FN3K CSNK1D LOC105376791 SECTM1 FOXK2 LOC101929552 MIR4525 UTS2R TEX19 ZNF750
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	FN3KRP CCDC57 NOTUM ANAPC11 LRRC45 PCYT2 METRNL SIRT7 LOC101929552 ZNF750 PYCR1 TBCD NARF P4HB C17orf62 B3GNTL1 MIR6787 HEXDC ARHGDIA LOC105376791 FOXK2 MAFG STRA13 WDR45B DCXR MYADML2 LOC105376790 GPS1 NPB PPP1R27 RFNG MAFG-AS1 ALYREF ASPSCR1 FN3K MCRIP1 MIR4525 FASN SNORD134 LOC101929511 DUS1L RAC3 RAB40B OGFOD3 SLC16A3 CD7 LOC105371944 CSNK1D SECTM1 UTS2R TEX19

More Information

Additional Information:

For this assay, SNP(s) [rs138867801] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

small GTPase mediated signal transduction
protein ubiquitination
symbiont intracellular protein transport in host

Function(s)

GTP binding