Mm00005222_cn

• Gene Symbol: Hlcs
• Assay Reference Genome Location: Chr.16:94138914 on build GRCm38
• Cytoband: 16C4

Target Gene Details

• Entrez Gene ID: 110948
• Gene Name: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
• Gene Aliases: 410I21.SP6, D16Jhu34
• Location: Chr.16:94129195-94313905 on Build GRCm38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Hlcs	NM_139145.4	7	1739	NP_631884.1
	AB066227.1	6	1599	BAB68213.1
	AK052424.1	8	2035
	AK158212.1	8	1856	BAE34407.1
	AK168925.1	4	634	BAE40738.1
	BC050090.1	7	1740	AAH50090.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

ligase

Gene Ontology Categories:

Process(es)

cellular protein modification process
metabolic process
cell proliferation
protein biotinylation
histone modification
response to biotin
histone biotinylation

Function(s)

nucleotide binding
catalytic activity
biotin-[acetyl-CoA-carboxylase] ligase activity
biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity
ATP binding
biotin binding
ligase activity
lipoate-protein ligase activity
biotin-protein ligase activity
enzyme binding
tRNA(Ile)-lysidine synthase activity
protein homodimerization activity
biotin-[pyruvate-carboxylase] ligase activity