Mm00160266_cn

• Gene Symbol: Rabgef1
• Assay Reference Genome Location: Chr.5:130207006 on build GRCm38
• Cytoband: 5G1.3

Target Gene Details

• Entrez Gene ID: 56715
• Gene Name: RAB guanine nucleotide exchange factor (GEF) 1
• Gene Aliases: Rab5ef, Rabex5, Rin2
• Location: Chr.5:130171791-130214342 on Build GRCm38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Rabgef1	NM_001199059.1			NP_001185988.1
	NM_019983.2			NP_064367.1
	AF093590.1			AAF28738.1
	AK044568.1			BAC31984.1
	AK146734.1			BAE27396.1
	BC018229.1			AAH18229.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
transport
endocytosis
protein transport
protein ubiquitination
negative regulation of mast cell activation
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
metal ion binding
ubiquitin protein ligase activity