Mm00182211_cn

• Gene Symbol: Cftr
• Assay Reference Genome Location: Chr.6:18282539 on build GRCm38
• Cytoband: 6A2

Target Gene Details

• Entrez Gene ID: 12638
• Gene Name: cystic fibrosis transmembrane conductance regulator
• Gene Aliases: AW495489, Abcc7
• Location: Chr.6:18170262-18322774 on Build GRCm38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Cftr	NM_021050.2	20	3374	NP_066388.1
	M60493.1	20	3375	AAA18903.1
	M69298.1	20	3373	AAA37417.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

cholesterol biosynthetic process
transport
ion transport
chloride transport
water transport
bicarbonate transport
iodide transport
cholesterol transport
transepithelial chloride transport
lung development
vasodilation
positive regulation of vasodilation
sperm capacitation
intracellular pH elevation
transmembrane transport
membrane hyperpolarization
cellular response to cAMP
chloride transmembrane transport
positive regulation of voltage-gated chloride channel activity

Function(s)

nucleotide binding
chloride channel activity
channel-conductance-controlling ATPase activity
protein binding
ATP binding
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
hydrolase activity
ATPase activity
chloride channel inhibitor activity
enzyme binding
PDZ domain binding
ATPase activity, coupled to transmembrane movement of substances