Mm00324964_cn

• Gene Symbol: Arrb2
• Assay Reference Genome Location: Chr.11:70436942 on build GRCm38
• Cytoband: 11B3

Target Gene Details

• Entrez Gene ID: 216869
• Gene Name: arrestin, beta 2
• Gene Aliases: AI326910, AW122872
• Location: Chr.11:70432580-70440828 on Build GRCm38
• Assay Gene Location: Overlaps Exon 6 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Arrb2	NM_001271358.1			NP_001258287.1
	NM_001271359.1			NP_001258288.1
	NM_001271360.1			NP_001258289.1
	NM_145429.5			NP_663404.1
	AK089542.1
	AK154874.1			BAE32894.1
	AK159317.1			BAE34984.1
	AK162889.1			BAE37102.1
	AK170647.1			BAE41934.1
	AK170889.1			BAE42096.1
	BC016642.1			AAH16642.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
positive regulation of protein phosphorylation
G-protein coupled receptor internalization
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
positive regulation of receptor internalization
transcription from RNA polymerase II promoter
transport
endocytosis
signal transduction
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
adult walking behavior
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of signal transduction
protein transport
protein ubiquitination
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
receptor internalization
negative regulation of NF-kappaB transcription factor activity
positive regulation of synaptic transmission, dopaminergic
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of peptidyl-serine phosphorylation
negative regulation of toll-like receptor signaling pathway
negative regulation of GTPase activity
negative regulation of smooth muscle cell apoptotic process
follicle-stimulating hormone signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
detection of temperature stimulus involved in sensory perception of pain
positive regulation of protein kinase B signaling
positive regulation of calcium ion transport
cell chemotaxis
regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of release of cytochrome c from mitochondria
positive regulation of DNA biosynthetic process

Function(s)

G-protein coupled receptor binding
receptor binding
protein binding
enzyme binding
protein domain specific binding
ubiquitin protein ligase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
angiotensin receptor binding
type 1 angiotensin receptor binding
D1 dopamine receptor binding
follicle-stimulating hormone receptor binding
type 2A serotonin receptor binding
platelet activating factor receptor binding
protein complex binding
protein complex scaffold
protein kinase B binding
mitogen-activated protein kinase binding
14-3-3 protein binding