Mm00373725_cn

• Gene Symbol: Esr2
• Assay Reference Genome Location: Chr.12:76140188 on build GRCm38
• Cytoband: 12C3

Target Gene Details

• Entrez Gene ID: 13983
• Gene Name: estrogen receptor 2 (beta)
• Gene Aliases: ER[b], ERbeta, Estrb
• Location: Chr.12:76120419-76177259 on Build GRCm38
• Assay Gene Location: Overlaps Intron 6 - Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Esr2	NM_010157.3			NP_034287.3
	NM_207707.1			NP_997590.1
	NR_104386.1
	AK054290.1			BAC35719.1
	AK054301.1
	AK054413.1			BAC35770.1
	AY054413.1			AAL15175.1
	BC141075.1
	BC145329.1
	U81451.1			AAB51132.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ovarian follicle development
behavioral fear response
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
brain development
learning or memory
negative regulation of cell proliferation
hormone-mediated apoptotic signaling pathway
intracellular steroid hormone receptor signaling pathway
intracellular estrogen receptor signaling pathway
response to testosterone
regulation of cell proliferation
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
regulation of neuron apoptotic process
estrous cycle
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of behavior
negative regulation of smooth muscle cell proliferation
negative regulation of epithelial cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
Sertoli cell proliferation
uterus development
vagina development
negative regulation of cell death
prostate gland epithelium morphogenesis
epithelial cell maturation involved in prostate gland development
negative regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of neuron death
negative regulation of feeding behavior
negative regulation of reactive oxygen species metabolic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
steroid binding
protein binding
drug binding
zinc ion binding
lipid binding
enzyme binding
estrogen receptor activity
estrogen response element binding
hormone binding
peroxisome proliferator activated receptor binding
sequence-specific DNA binding
metal ion binding
estradiol binding
steroid hormone binding