Mm00400431_cn

• Gene Symbol: Ripk1
• Assay Reference Genome Location: Chr.13:34002912 on build GRCm38
• Cytoband: 13A3.3

Target Gene Details

• Entrez Gene ID: 19766
• Gene Name: receptor (TNFRSF)-interacting serine-threonine kinase 1
• Gene Aliases: D330015H01Rik, RIP, Rinp, Rip1
• Location: Chr.13:34000844-34035170 on Build GRCm38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ripk1	NM_009068.3	1	39	NP_033094.3
	AK030959.1			BAC27194.1
	AK048989.1
	AK156803.1			BAE33860.1
	BC050905.1	1	39	AAH50905.2
	BC054542.1	1	39	AAH54542.1
	BC058162.1			AAH58162.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
protein phosphorylation
apoptotic process
signal transduction
positive regulation of cell death
programmed cell death
viral process
phosphorylation
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
response to tumor necrosis factor
peptidyl-serine autophosphorylation
positive regulation of phosphorylation
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
cellular protein catabolic process
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of transferase activity
positive regulation of necroptotic process
T cell apoptotic process
necroptotic process
regulation of ATP:ADP antiporter activity
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
extrinsic apoptotic signaling pathway
ripoptosome assembly
necroptotic signaling pathway
ripoptosome assembly involved in necroptotic process
amyloid fibril formation
regulation of reactive oxygen species metabolic process
negative regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
death receptor binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
ubiquitin protein ligase binding
protein complex binding
identical protein binding
death domain binding