Mm00515703_cn

• Gene Symbol: Flna
• Assay Reference Genome Location: Chr.X:74228189 on build GRCm38
• Cytoband: XA7.3

Target Gene Details

• Entrez Gene ID: 192176
• Gene Name: filamin, alpha
• Gene Aliases: ABP-280, Dilp2, F730004A14Rik, Fln1, GENA 379, filamin-1
• Location: Chr.X:74223461-74249854 on Build GRCm38
• Assay Gene Location: Within Exon 38

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Flna	NM_001290421.1	38	6372	NP_001277350.1
	NM_010227.3	37	6350	NP_034357.2
	AF353671.1	1	51	AAL68447.1
	AK131179.1	25	4191	BAD21429.1
	BC151024.1	37	6341

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

epithelial to mesenchymal transition
adenylate cyclase-inhibiting dopamine receptor signaling pathway
negative regulation of transcription from RNA polymerase I promoter
cell projection organization
actin cytoskeleton organization
actin cytoskeleton reorganization
protein localization to cell surface
negative regulation of protein catabolic process
cilium assembly
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription factor import into nucleus
negative regulation of apoptotic process
receptor clustering
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of sequence-specific DNA binding transcription factor activity
early endosome to late endosome transport
establishment of protein localization
protein stabilization
cytoplasmic sequestering of protein
actin crosslink formation
platelet aggregation
mitotic spindle assembly
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of integrin-mediated signaling pathway

Function(s)

glycoprotein binding
actin binding
signal transducer activity
protein kinase C binding
protein binding
transcription factor binding
Rho GTPase binding
Ral GTPase binding
small GTPase binding
mu-type opioid receptor binding
protein complex binding
Fc-gamma receptor I complex binding
protein homodimerization activity
poly(A) RNA binding
SMAD binding
Rac GTPase binding
actin filament binding