Mm00538176_cn

• Gene Symbol: Ptgis
• Assay Reference Genome Location: Chr.2:167203277 on build GRCm38
• Cytoband: 2H3

Target Gene Details

• Entrez Gene ID: 19223
• Gene Name: prostaglandin I2 (prostacyclin) synthase
• Gene Aliases: Cyp8, Cyp8a1, Pgis
• Location: Chr.2:167203194-167252127 on Build GRCm38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ptgis	NM_008968.3	10	1670	NP_032994.1
	AB001607.1	10	1588	BAA21717.1
	AK076585.1	10	1671	BAC36403.1
	BC062151.1	10	1677	AAH62151.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
response to hypoxia
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
prostaglandin metabolic process
embryo implantation
negative regulation of NF-kappaB transcription factor activity
positive regulation of peroxisome proliferator activated receptor signaling pathway
regulation of apoptotic process
negative regulation of nitric oxide biosynthetic process
positive regulation of angiogenesis
decidualization
negative regulation of inflammatory response
oxidation-reduction process
cellular response to hypoxia
apoptotic signaling pathway
positive regulation of execution phase of apoptosis

Function(s)

monooxygenase activity
iron ion binding
prostaglandin-I synthase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
isomerase activity
heme binding
metal ion binding