Mm00594522_cn

• Gene Symbol: Nf2
• Assay Reference Genome Location: Chr.11:4767865 on build GRCm38
• Cytoband: 11A1

Target Gene Details

• Entrez Gene ID: 18016
• Gene Name: neurofibromatosis 2
• Gene Aliases: merlin
• Location: Chr.11:4757650-4849544 on Build GRCm38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Nf2	NM_001252250.1	17	2753	NP_001239179.1
	NM_001252252.1	16	2724	NP_001239181.1
	NM_010898.4	16	2708	NP_035028.2
	AK161134.1	1	3327
	AK167685.1	13	1799	BAE39732.1
	BC005442.1			AAH05442.1
	L27090.1	16	2159	AAA63648.1
	L27105.1	17	2204	AAA39807.1
	X75759.1	6	997	CAA53386.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

mesoderm formation
negative regulation of protein kinase activity
ectoderm development
brain development
negative regulation of DNA replication
negative regulation of cell proliferation
Schwann cell proliferation
regulation of gliogenesis
hippocampus development
negative regulation of cell-cell adhesion
actin cytoskeleton organization
negative regulation of cell growth
regulation of protein stability
regulation of hippo signaling
regulation of cell proliferation
odontogenesis of dentin-containing tooth
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of MAPK cascade
cell-cell junction organization
positive regulation of cell differentiation
negative regulation of JAK-STAT cascade
regulation of neurogenesis
positive regulation of stress fiber assembly
lens fiber cell differentiation
regulation of stem cell proliferation
regulation of protein localization to nucleus
regulation of neural precursor cell proliferation

Function(s)

actin binding
integrin binding
protein binding
beta-catenin binding
cytoskeletal protein binding
protein domain specific binding