Mm00610858_cn

• Gene Symbol: Shank3
• Assay Reference Genome Location: Chr.15:89521288 on build GRCm38
• Cytoband: 15E3

Target Gene Details

• Entrez Gene ID: 58234
• Gene Name: SH3/ankyrin domain gene 3
• Gene Aliases: AI841104, SHANK3c-3, SHANK3c-4, Shank3b
• Location: Chr.15:89499707-89560261 on Build GRCm38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Shank3	NM_021423.3	10	1216	NP_067398.2
	AB231013.1	10	1216	BAE16756.1
	AJ245904.1	8	1070	CAB89816.1
	HQ405764.1
	HQ405765.1
	HQ405766.1
	KF612592.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

MAPK cascade
embryonic epithelial tube formation
synapse assembly
learning
memory
striatal medium spiny neuron differentiation
adult behavior
negative regulation of actin filament bundle assembly
social behavior
locomotory exploration behavior
vocal learning
negative regulation of cell volume
positive regulation of long-term neuronal synaptic plasticity
brain morphogenesis
neuromuscular process controlling balance
protein oligomerization
positive regulation of synapse structural plasticity
positive regulation of synaptic transmission, glutamatergic
dendritic spine morphogenesis
positive regulation of dendritic spine development
regulation of dendritic spine morphogenesis
vocalization behavior
postsynaptic density assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
guanylate kinase-associated protein clustering
regulation of long-term synaptic potentiation
positive regulation of long-term synaptic potentiation
positive regulation of glutamate receptor signaling pathway
regulation of long term synaptic depression
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior
regulation of behavioral fear response
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Function(s)

actin binding
protein binding
protein C-terminus binding
zinc ion binding
SH3 domain binding
GKAP/Homer scaffold activity
ionotropic glutamate receptor binding
identical protein binding
protein self-association
scaffold protein binding