Mm00618072_cn

• Gene Symbol: Dab2
• Assay Reference Genome Location: Chr.15:6439415 on build GRCm38
• Cytoband: 15A1

Target Gene Details

• Entrez Gene ID: 13132
• Gene Name: disabled 2, mitogen-responsive phosphoprotein
• Gene Aliases: 5730435J12Rik, AA960054, AI957090, D15Wsu122e, D630005B22Rik, Doc-2, Doc2, p96
• Location: Chr.15:6299788-6440715 on Build GRCm38
• Assay Gene Location: Within Exon 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Dab2	NM_001008702.2	14	2495	NP_001008702.1
	NM_001037905.3	14	2569	NP_001032994.1
	NM_001102400.1	13	2506	NP_001095870.1
	NM_023118.5	15	3223	NP_075607.2
	AK154716.1	15	3207	BAE32784.1
	AK162744.1	13	2477	BAE37047.1
	AK162851.1	14	2540	BAE37084.1
	AK165519.1	14	2453	BAE38234.1
	AK165810.1	14	2450	BAE38389.1
	AK168375.1	14	2542
	BC006588.1	13	2390	AAH06588.1
	BC016887.1	14	2435	AAH16887.1
	U18869.1	15	3156	AAB02646.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

cell morphogenesis involved in differentiation
in utero embryonic development
positive regulation of receptor recycling
positive regulation of protein phosphorylation
transport
endocytosis
receptor-mediated endocytosis
pinocytosis
apoptotic process
activation of JUN kinase activity
multicellular organism development
endoderm development
excretion
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of neuron projection development
protein transport
Wnt signaling pathway
cell differentiation
negative regulation of cell growth
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
positive regulation of aldosterone biosynthetic process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of transcription elongation from RNA polymerase II promoter
leading edge cell differentiation
negative regulation of apoptotic process
positive regulation of cell adhesion
positive regulation of endocytosis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
clathrin coat assembly
response to steroid hormone
negative regulation of epithelial cell proliferation
positive regulation of SMAD protein import into nucleus
negative regulation of androgen receptor signaling pathway
negative regulation of ERK1 and ERK2 cascade
cellular response to epidermal growth factor stimulus
cellular response to transforming growth factor beta stimulus
negative regulation of canonical Wnt signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of protein localization to plasma membrane
positive regulation of Wnt signaling pathway, planar cell polarity pathway
regulation of Rho-dependent protein serine/threonine kinase activity
positive regulation of clathrin-mediated endocytosis
positive regulation of early endosome to late endosome transport
positive regulation of aldosterone secretion
positive regulation of integrin-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

integrin binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
protein C-terminus binding
clathrin binding
phosphatidylinositol binding
AP-2 adaptor complex binding
clathrin adaptor activity
cargo receptor activity
SMAD binding