Mm00733736_cn

• Gene Symbol: Fadd
• Assay Reference Genome Location: Chr.7:144581237 on build GRCm38
• Cytoband: 7F5

Target Gene Details

• Entrez Gene ID: 14082
• Gene Name: Fas (TNFRSF6)-associated via death domain
• Gene Aliases: Mort1/FADD
• Location: Chr.7:144578323-144582436 on Build GRCm38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Fadd	NM_010175.5			NP_034305.1
	AK007648.1
	AK031396.1			BAC27384.1
	AK084808.1			BAC39283.1
	AK169798.1			BAE41374.1
	AK170927.1			BAE42120.1
	BC004584.1			AAH04584.1
	BC021400.1			AAH21400.1
	U43184.1			AAA97876.1
	U50406.1			AAB07789.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, Validated

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
immune system process
positive regulation of adaptive immune response
apoptotic process
signal transduction
T cell differentiation
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
T cell differentiation in thymus
TRAIL-activated apoptotic signaling pathway
positive regulation of activated T cell proliferation
regulation of apoptotic process
T cell homeostasis
positive regulation of apoptotic process
innate immune response
positive regulation of macrophage differentiation
positive regulation of proteolysis
positive regulation of transcription from RNA polymerase II promoter
lymph node development
spleen development
thymus development
cardiac muscle tissue development
protein heterooligomerization
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
negative regulation of necroptotic process
negative regulation of activation-induced cell death of T cells
motor neuron apoptotic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
necroptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
tumor necrosis factor receptor binding
protein binding
protein complex binding
tumor necrosis factor receptor superfamily binding
death effector domain binding
identical protein binding