Mm00735014_cn

• Gene Symbol: Pink1
• Assay Reference Genome Location: Chr.4:138319832 on build GRCm38
• Cytoband: 4D3

Target Gene Details

• Entrez Gene ID: 68943
• Gene Name: PTEN induced putative kinase 1
• Gene Aliases: 1190006F07Rik, AU042772, AW557854, BRPK, mFLJ00387
• Location: Chr.4:138313409-138326296 on Build GRCm38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Pink1	NM_026880.2			NP_081156.2
	AB053476.1			BAB55651.1
	AF316872.1			AAK28061.1
	AK050322.1
	AK155474.1			BAE33284.1
	AK165480.1
	AK188455.1
	AK215426.1
	AK220318.1			BAD90392.1
	BC067066.1			AAH67066.1
	BC069968.1			AAH69968.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, Validated

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

mitophagy
positive regulation of protein phosphorylation
regulation of oxidative phosphorylation
protein phosphorylation
autophagy
response to stress
response to oxidative stress
mitochondrion organization
regulation of hydrogen peroxide metabolic process
negative regulation of gene expression
regulation of mitochondrion organization
positive regulation of macroautophagy
negative regulation of macroautophagy
phosphorylation
protein ubiquitination
peptidyl-serine phosphorylation
respiratory electron transport chain
regulation of protein ubiquitination
positive regulation of synaptic transmission, dopaminergic
positive regulation of peptidyl-serine phosphorylation
positive regulation of dopamine secretion
positive regulation of catecholamine secretion
cellular response to oxidative stress
positive regulation of protein dephosphorylation
intracellular signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of protein complex assembly
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
positive regulation of translation
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of mitochondrial membrane potential
cellular response to hypoxia
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
negative regulation of mitochondrial fission
cellular response to toxic substance
mitophagy in response to mitochondrial depolarization
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of autophagosome assembly
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of mitophagy
negative regulation of oxidative stress-induced cell death
regulation of protein targeting to mitochondrion
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of cristae formation
positive regulation of protein targeting to mitochondrion
regulation of reactive oxygen species metabolic process
negative regulation of reactive oxygen species metabolic process

Function(s)

nucleotide binding
magnesium ion binding
protease binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
calcium-dependent protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
ubiquitin protein ligase binding
protein kinase B binding
metal ion binding
C3HC4-type RING finger domain binding