Hs00070343_cn

• Gene Symbol: DUOX2
• Assay Reference Genome Location: Chr.15:45105824 on build GRCh38
• Cytoband: 15q21.1

Target Gene Details

• Entrez Gene ID: 50506
• Gene Name: dual oxidase 2
• Gene Aliases: LNOX2, NOXEF2, P138-TOX, TDH6, THOX2
• Location: Chr.15:45092653-45114161 on Build GRCh38
• Assay Gene Location: Overlaps Intron 17 - Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DUOX2	NM_014080.4			NP_054799.4
	XM_005254421.2			XP_005254478.1
	AB209010.1			BAD92247.1
	AF181972.1			AAF20055.1
	AF230496.1			AAF73922.1
	AF267981.1			AAF78954.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv569312	Chr.15:45089800 - 45168224 on Build GRCh38	Loss	DUOXA1 DUOX1 DUOXA2 SHF DUOX2
esv2760029	Chr.15:44676670 - 45130644 on Build GRCh38	Gain+Loss	PATL2 DUOXA1 DUOX1 DUOXA2 LOC100419583 SORD TRIM69 B2M TERB2 DUOX2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

thyroid hormone generation
response to oxidative stress
fertilization
response to virus
cytokine-mediated signaling pathway
bone mineralization
thyroid gland development
multicellular organism growth
cuticle development
hormone biosynthetic process
hydrogen peroxide catabolic process
inner ear development
adenohypophysis morphogenesis
hydrogen peroxide biosynthetic process
response to cAMP
oxidation-reduction process
cellular oxidant detoxification

Function(s)

peroxidase activity
calcium ion binding
NAD(P)H oxidase activity
heme binding