Hs00169560_cn

• Gene Symbol: ETS2
• Assay Reference Genome Location: Chr.21:38810065 on build GRCh38
• Cytoband: 21q22.2

Target Gene Details

• Entrez Gene ID: 2114
• Gene Name: ETS proto-oncogene 2, transcription factor
• Gene Aliases: ETS2IT1
• Location: Chr.21:38805307-38824955 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ETS2	NM_001256295.1			NP_001243224.1
	NM_005239.5			NP_005230.1
	XM_005260935.1			XP_005260992.1
	XM_017028290.1			XP_016883779.1
	AK096841.1
	AK315563.1
	AY216265.1	1	1956
	BC017040.1			AAH17040.1
	BC042954.2			AAH42954.1
	BT006838.1			AAP35484.1
	J04102.1			AAA52412.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3518	Chr.21:38809536 - 38843702 on Build GRCh38	Insertion	ETS2
nsv1058591	Chr.21:38742206 - 38818670 on Build GRCh38	Gain	LINC00114 ETS2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
ectodermal cell fate commitment
transcription, DNA-templated
mesoderm development
cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
primitive streak formation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
glucocorticoid receptor binding