Hs00183887_cn

• Gene Symbol: LOC339059
• Assay Reference Genome Location: Chr.16:88743093 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 339059
• Gene Name: uncharacterized LOC339059
• Gene Aliases: -
• Location: Chr.16:88742767-88745748 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC339059	NR_120387.1	1	327
	AK097767.1	1	327	BAC05165.1
	BC111769.1	1	273	AAI11770.1

Target Gene Details

• Entrez Gene ID: 9780
• Gene Name: piezo type mechanosensitive ion channel component 1
• Gene Aliases: DHS, FAM38A, LMPH3, Mib
• Location: Chr.16:88715338-88785220 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIEZO1	NM_001142864.3			NP_001136336.2
	HY165228.1
	KC602455.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC339059 CDH15 LOC100289580 GALNS LOC105371409 CBFA2T3 TRAPPC2L APRT SLC22A31 LOC101927793 MIR4722 ACSF3 PIEZO1 LOC400558 ZNF778 CTU2 LINC00304 CDT1 LOC100129697 PABPN1L LOC107987238
nsv471113	Chr.16:88650665 - 88764428 on Build GRCh38	Loss	PIEZO1 LOC339059 LOC100289580 MVD SNAI3-AS1 CTU2 SNAI3 MIR4722 RNF166 CYBA
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	PIEZO1 LOC339059 LOC100289580 GALNS SNAI3-AS1 CTU2 APRT CDT1 SNAI3 MIR4722 RNF166 LOC107987238
nsv517643	Chr.16:88713767 - 88756339 on Build GRCh38	Loss	PIEZO1 LOC339059 LOC100289580 CTU2 MIR4722
nsv833327	Chr.16:88667431 - 88757621 on Build GRCh38	Loss	PIEZO1 LOC339059 LOC100289580 SNAI3-AS1 CTU2 SNAI3 MIR4722 RNF166
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC339059 CDH15 LOC100289580 GALNS LOC100287036 LOC105371409 CBFA2T3 TRAPPC2L LOC105371414 APRT SLC22A31 LOC101927793 ACSF3 PIEZO1 LOC400558 ANKRD11 ZNF778 LINC00304 CDT1 LOC100129697 PABPN1L LOC107987238
nsv1927	Chr.16:88712585 - 88743583 on Build GRCh38	Insertion	PIEZO1 LOC339059 LOC100289580 CTU2 MIR4722
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	FANCA LOC100289580 LOC100287036 LOC105371409 CBFA2T3 TRAPPC2L ACSF3 CYBA TCF25 SPATA2L DPEP1 CPNE7 SNORD68 TUBB8P7 MC1R LOC339059 CDH15 LOC107984817 RPL13 ZNF276 VPS9D1-AS1 ZNF778 CTU2 SPG7 FAM157C CDT1 GAS8-AS1 LOC105371419 RNF166 PABPN1L LOC101927817 CDK10 GALNS PRDM7 LOC105371414 SNAI3 DBNDD1 LOC101927793 MIR4722 PIEZO1 LOC400558 MVD SPIRE2 GAS8 LOC100129697 DEF8 IL17C VPS9D1 CHMP1A APRT SLC22A31 AFG3L1P CENPBD1 URAHP TUBB3 ANKRD11 SNAI3-AS1 LINC00304 LOC107987238 SPATA33
nsv471114	Chr.16:88688461 - 88756339 on Build GRCh38	Gain	PIEZO1 LOC339059 LOC100289580 CTU2 MIR4722 RNF166
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	IL17C LOC339059 LOC100289580 ZFPM1 SNAI3 MIR4722 ZC3H18-AS1 CYBA ZC3H18 PIEZO1 ZNF469 MVD SNAI3-AS1 LOC107984862 CTU2 MIR5189 RNF166
nsv1160442	Chr.16:88708161 - 88778524 on Build GRCh38	Deletion	PIEZO1 LOC339059 LOC100289580 CTU2 MIR4722
dgv3065n100	Chr.16:88711587 - 88927172 on Build GRCh38	Gain	LOC339059 LOC100289580 GALNS CBFA2T3 TRAPPC2L APRT LOC101927793 MIR4722 PIEZO1 CTU2 CDT1 PABPN1L LOC107987238
nsv573675	Chr.16:88740797 - 88743485 on Build GRCh38	Loss	PIEZO1 LOC339059 LOC100289580

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cation transport
positive regulation of integrin activation
positive regulation of cell-cell adhesion mediated by integrin
cation transmembrane transport

Function(s)

cation channel activity
mechanically-gated ion channel activity