Hs00218660_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82831098 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	2	1668	NP_078978.2
	AK023903.1	2	1637	BAB14718.1
	AK301690.1	2	485
	BC109036.1	2	1627	AAI09037.1
	BC109037.1	2	1627	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	ZNF750 B3GNTL1 METRNL LOC105376791 WDR45B FN3KRP FOXK2 RAB40B LOC101929552 MIR4525 TBCD FN3K LOC105371944
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	ZNF750 RAB40B LOC105376791 LOC101929552 MIR4525 TBCD FN3K FN3KRP
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	NPB P4HB TSPAN10 ASPSCR1 DUS1L CCDC57 LOC100130370 MRPL12 PCYT2 FOXK2 OGFOD3 ACTG1 GCGR SIRT7 LRRC45 MCRIP1 UTS2R B3GNTL1 NPLOC4 FAAP100 ARL16 WDR45B SECTM1 DCXR CEP131 PYCR1 C17orf62 OXLD1 BAHCC1 CSNK1D FSCN2 MIR4740 MAFG HEXDC MIR3186 TMEM105 LINC00482 ARHGDIA ANAPC11 AATK MIR4525 MAFG-AS1 RFNG AATK-AS1 GPS1 FN3K C17orf89 RAC3 LOC101929511 PDE6G ZNF750 TEPSIN LOC105376791 CD7 CCDC137 SLC38A10 RAB40B ALYREF TBCD LOC105371944 SLC25A10 LOC105376790 TEX19 STRA13 MYADML2 HGS FN3KRP LOC105371925 MIR6786 NOTUM NARF LOC101929552 MIR6787 FASN SLC16A3 PPP1R27 SNORD134
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	ZNF750 TBCD
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	ZNF750 TBCD
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	ZNF750 LOC105376790 TEX19 LOC105376791 CD7 WDR45B SECTM1 C17orf62 FN3KRP CSNK1D FOXK2 OGFOD3 HEXDC RAB40B NARF LOC101929552 MIR4525 TBCD FN3K LOC101929511 UTS2R
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	NPB P4HB ASPSCR1 DUS1L CCDC57 PCYT2 FOXK2 OGFOD3 SIRT7 LRRC45 MCRIP1 UTS2R B3GNTL1 WDR45B SECTM1 DCXR PYCR1 C17orf62 CSNK1D MAFG HEXDC ARHGDIA ANAPC11 MIR4525 MAFG-AS1 RFNG GPS1 FN3K RAC3 LOC101929511 ZNF750 LOC105376791 CD7 RAB40B ALYREF TBCD LOC105371944 METRNL LOC105376790 TEX19 STRA13 MYADML2 FN3KRP NOTUM NARF LOC101929552 MIR6787 FASN SLC16A3 PPP1R27 SNORD134

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding