Hs00303028_cn

• Gene Symbol: ABCB1
• Assay Reference Genome Location: Chr.7:87531380 on build GRCh38
• Cytoband: 7q21.12

Target Gene Details

• Entrez Gene ID: 5243
• Gene Name: ATP binding cassette subfamily B member 1
• Gene Aliases: ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1
• Location: Chr.7:87503863-87713323 on Build GRCh38
• Assay Gene Location: Within Exon 22

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ABCB1	NM_000927.4	22	3092	NP_000918.2
	AB208970.1	20	2562	BAD92207.1
	AF016535.1	21	2715	AAB69423.1
	AK290159.1	22	3093
	AK308467.1	2	241
	BC130424.1	21	2924
	BQ720763.1	3	267
	EU852583.1	20	2599
	EU854148.1	19	2407
	M14758.1	22	3023	AAA59575.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv464622	Chr.7:87203287 - 87911933 on Build GRCh38	Gain	ABCB4 RUNDC3B CROT DBF4 SLC25A40 TP53TG1 TMEM243 ABCB1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
positive regulation of antigen processing and presentation of peptide antigen via MHC class I
transport
drug transmembrane transport
response to drug
xenobiotic transport
transmembrane transport
stem cell proliferation

Function(s)

transporter activity
protein binding
ATP binding
xenobiotic-transporting ATPase activity
ATPase activity, coupled to transmembrane movement of substances