Hs00405077_cn

• Gene Symbol: ELMO3
• Assay Reference Genome Location: Chr.16:67199389 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 79767
• Gene Name: engulfment and cell motility 3
• Gene Aliases: CED-12, CED12, ELMO-3
• Location: Chr.16:67199125-67204024 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ELMO3	NM_024712.3			NP_078988.2
	AK056923.1
	AK300976.1
	DA872517.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	NRN1L ELMO3 HSD11B2 FHOD1 NUTF2 CENPT LOC105369155 ENKD1 TPPP3 CTCF ACD FBXL8 PLEKHG4 AGRP CARMIL2 EXOC3L1 FAM65A EDC4 GFOD2 PARD6A HSF4 TMEM208 E2F4 NOL3 RANBP10 LOC107984813 LOC100505942 KIAA0895L DPEP2 PSKH1 DDX28 DPEP3 ATP6V0D1 KCTD19 THAP11 LRRC36 LOC100131303 PSMB10 LCAT LRRC29 C16orf86 DUS2 SLC12A4 SLC9A5 TRADD MIR328 TSNAXIP1 ZDHHC1 CTRL
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	ELMO3 TMEM208 LRRC29 E2F4 NOL3 FHOD1 LOC105369155 C16orf70 KIAA0895L B3GNT9 SLC9A5 FBXL8 TRADD PLEKHG4 EXOC3L1 MIR328 HSF4
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	ELMO3 TMEM208 LRRC29 E2F4 NOL3 FHOD1 LOC105369155 C16orf70 KIAA0895L B3GNT9 FBXL8 TRADD EXOC3L1 MIR328 HSF4
nsv1160429	Chr.16:67161549 - 67220197 on Build GRCh38	Deletion	ELMO3 LRRC29 E2F4 FBXL8 NOL3 EXOC3L1 MIR328 LOC105369155 KIAA0895L HSF4
nsv457513	Chr.16:67181417 - 67282697 on Build GRCh38	Loss	ELMO3 TMEM208 LRRC29 SLC9A5 E2F4 FHOD1 PLEKHG4 EXOC3L1 MIR328 LOC105369155 KIAA0895L
nsv524492	Chr.16:67174030 - 67294550 on Build GRCh38	Loss	ELMO3 TMEM208 LRRC29 E2F4 NOL3 FHOD1 LOC105369155 KCTD19 KIAA0895L SLC9A5 PLEKHG4 EXOC3L1 MIR328
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	NRN1L ELMO3 HSD11B2 FHOD1 NUTF2 CENPT LOC105369155 ENKD1 C16orf70 TPPP3 CTCF ACD FBXL8 PLEKHG4 AGRP CARMIL2 EXOC3L1 FAM65A EDC4 GFOD2 PARD6A HSF4 TMEM208 E2F4 NOL3 RANBP10 LOC107984813 LOC100505942 KIAA0895L B3GNT9 DPEP2 PSKH1 DDX28 DPEP3 ATP6V0D1 KCTD19 THAP11 LRRC36 LOC100131303 PSMB10 LCAT LRRC29 C16orf86 DUS2 SLC12A4 SLC9A5 TRADD MIR328 TSNAXIP1 ZDHHC1 CTRL

More Information

Additional Information:

For this assay, SNP(s) [rs75193761] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

phagocytosis
apoptotic process
cell migration

Function(s)

protein binding
SH3 domain binding