Hs00405557_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143991776 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Exon 3 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 GRINA PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	KIFC2 MIR6849 SCX SCRT1 FOXH1 ADCK5 MIR6893 HGH1 RECQL4 GPAA1 LOC101928953 VPS28 MIR6846 MFSD3 MAF1 PPP1R16A PARP10 LOC101928902 WDR97 MIR6848 MROH1 GPT MIR661 MIR6847 CYHR1 DGAT1 HSF1 SPATC1 TONSL-AS1 GRINA MIR1234 MIR939 SLC52A2 SHARPIN BOP1 TONSL CPSF1 TMEM249 CYC1 SLC39A4 EXOSC4 SMPD5 FBXL6 LRRC14 PLEC MIR7112 OPLAH
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	KIFC2 MIR6849 SCX SCRT1 FOXH1 ADCK5 MIR6893 HGH1 RECQL4 GPAA1 LOC101928953 VPS28 MIR6846 MFSD3 MAF1 PPP1R16A PARP10 LOC101928902 WDR97 MIR6848 MROH1 GPT MIR661 MIR6847 CYHR1 DGAT1 HSF1 SPATC1 TONSL-AS1 GRINA MIR1234 MIR939 SLC52A2 SHARPIN BOP1 TONSL CPSF1 TMEM249 CYC1 SLC39A4 EXOSC4 SMPD5 FBXL6 LRRC14 PLEC MIR7112 OPLAH
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	MIR6847 SPATC1 GRINA GPAA1 SHARPIN MIR6846 MAF1 PARP10 CYC1 WDR97 EXOSC4 SMPD5 PLEC OPLAH
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	MIR661 MIR6847 EPPK1 SPATC1 GRINA HGH1 GPAA1 SHARPIN MIR6846 MAF1 PARP10 CYC1 WDR97 EXOSC4 SMPD5 PLEC MROH1 OPLAH
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	MIR661 MIR6847 EPPK1 SPATC1 GRINA GPAA1 SHARPIN MIR6846 MAF1 PARP10 CYC1 WDR97 EXOSC4 SMPD5 PLEC OPLAH
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	MIR661 MIR6847 PUF60 EPPK1 MIR937 SPATC1 GRINA SCRIB LOC642574 NRBP2 MIR6846 PARP10 MIR6845 EXOSC4 SMPD5 PLEC OPLAH
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	MIR661 MIR6847 MIR6846 SPATC1 PARP10 CYC1 GRINA EXOSC4 SMPD5 PLEC OPLAH GPAA1
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	MIR661 MIR6847 SPATC1 GRINA GPAA1 SHARPIN MIR6846 MAF1 PARP10 CYC1 WDR97 EXOSC4 SMPD5 PLEC OPLAH
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	MIR661 MIR6847 MIR6846 SPATC1 PARP10 GRINA EXOSC4 SMPD5 PLEC OPLAH GPAA1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding