Hs00420760_cn

• Gene Symbol: GLIS1
• Assay Reference Genome Location: Chr.1:53506333 on build GRCh38
• Cytoband: 1p32.3

Target Gene Details

• Entrez Gene ID: 148979
• Gene Name: GLIS family zinc finger 1
• Gene Aliases: -
• Location: Chr.1:53506233-53739171 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLIS1	NM_147193.2	10	2716	NP_671726.2
	XM_017000408.1	11	2783	XP_016855897.1
	XM_017000409.1	11	2771	XP_016855898.1
	XM_017000410.1	11	2897	XP_016855899.1
	XM_017000411.1	9	2436	XP_016855900.1
	AK090634.1	10	2715	BAC03494.1
	AK093474.1	8	2085	BAC04178.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv527806	Chr.1:53499393 - 53510515 on Build GRCh38	Loss	GLIS1
nsv522165	Chr.1:53506376 - 53539387 on Build GRCh38	Loss	GLIS1
nsv428443	Chr.1:53452879 - 53563563 on Build GRCh38	Gain	DMRTB1 GLIS1
nsv509269	Chr.1:53296636 - 53583096 on Build GRCh38	Insertion	LRP8 SLC25A3P1 DMRTB1 LOC105378732 GLIS1
nsv888	Chr.1:53471532 - 53508621 on Build GRCh38	Deletion	GLIS1
nsv829882	Chr.1:53449992 - 53629940 on Build GRCh38	Loss	DMRTB1 GLIS1

More Information

Additional Information:

For this assay, SNP(s) [rs72893308] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
metal ion binding