Hs00506659_cn

• Gene Symbol: CLCN6
• Assay Reference Genome Location: Chr.1:11806079 on build GRCh38
• Cytoband: 1p36.22

Target Gene Details

• Entrez Gene ID: 1185
• Gene Name: chloride voltage-gated channel 6
• Gene Aliases: CLC-6
• Location: Chr.1:11806096-11843144 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CLCN6	NM_001256959.1			NP_001243888.1
	NM_001286.3			NP_001277.1
	NR_046428.1
	DA229615.1

Target Gene Details

• Entrez Gene ID: 4524
• Gene Name: methylenetetrahydrofolate reductase (NAD(P)H)
• Gene Aliases: -
• Location: Chr.1:11785730-11806103 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MTHFR	NM_005957.4			NP_005948.3
	XM_005263460.4			XP_005263517.1
	XM_005263463.3			XP_005263520.1
	AY046560.1	1	842	AAL17646.1

More Information

• Set Membership: Intragenic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

ion channel, reductase

Gene Ontology Categories:

Process(es)

chloride transport
cell volume homeostasis
signal transduction
response to mechanical stimulus
ion transmembrane transport
chloride transmembrane transport
regulation of anion transmembrane transport
response to hypoxia
cellular amino acid metabolic process
methionine metabolic process
blood circulation
regulation of histone methylation
response to vitamin B2
tetrahydrofolate interconversion
response to drug
response to amino acid
S-adenosylmethionine metabolic process
folic acid metabolic process
homocysteine metabolic process
response to folic acid
oxidation-reduction process
response to interleukin-1
heterochromatin maintenance

Function(s)

voltage-gated chloride channel activity
ATP binding
antiporter activity
chloride ion binding
methylenetetrahydrofolate reductase (NAD(P)H) activity
protein complex binding
flavin adenine dinucleotide binding
NADP binding
modified amino acid binding