Hs00510838_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37127913 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3	10	1970	NP_000869.1
	BC025691.1	10	1953	AAH25691.1
	M26062.1	10	1970	AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	CYTH4 LOC101927051 LOC100506271 ELFN2 PDXP TST MPST NOL12 TMPRSS6 C1QTNF6 MFNG GGA1 LGALS1 SH3BP1 CARD10 LOC102724378 KCTD17 CDC42EP1 SSTR3 IL2RB LGALS2 TRIOBP TEX33 RAC2
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	KCTD17 TST IL2RB MPST TMPRSS6 LL22NC01-81G9.3 TEX33
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	KCTD17 TST IL2RB MPST TMPRSS6 LL22NC01-81G9.3 C1QTNF6 TEX33
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	KCTD17 TST IL2RB MPST TMPRSS6 LL22NC01-81G9.3 TEX33

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding