Hs00526589_cn

• Gene Symbol: NAGS
• Assay Reference Genome Location: Chr.17:44007709 on build GRCh38
• Cytoband: 17q21.31

Target Gene Details

• Entrez Gene ID: 162417
• Gene Name: N-acetylglutamate synthase
• Gene Aliases: AGAS, ARGA
• Location: Chr.17:44004546-44009068 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NAGS	NM_153006.2	6	1387	NP_694551.1
	XM_011524438.1			XP_011522740.1
	XM_011524439.2	6	1277	XP_011522741.1
	AK074407.1	6	1317
	AK091938.1	3	1275
	AK300923.1	7	1293
	AK314432.1	6	1505
	AY116538.1	6	1387	AAM75386.1
	AY158070.1	6	1108	AAN76451.1
	BC111713.1	7	1173	AAI11714.1

Target Gene Details

• Entrez Gene ID: 5697
• Gene Name: peptide YY
• Gene Aliases: PYY-I, PYY1
• Location: Chr.17:43952733-44024260 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PYY	XM_011525035.1			XP_011523337.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833454	Chr.17:43940848 - 44158311 on Build GRCh38	Loss	NAGS PYY LSM12 HDAC5 TMEM101 C17orf53 PPY LOC105371789 G6PC3

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

intercellular signal molecule

Gene Ontology Categories:

Process(es)

urea cycle
arginine biosynthetic process
glutamate metabolic process
movement of cell or subcellular component
cytoskeleton organization
G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
digestion
feeding behavior
cell proliferation
regulation of appetite
eating behavior

Function(s)

acetylglutamate kinase activity
acetyl-CoA:L-glutamate N-acetyltransferase activity
arginine binding
G-protein coupled receptor binding
hormone activity
neuropeptide hormone activity
protein binding