Hs00530553_cn

• Gene Symbol: SERPINA3
• Assay Reference Genome Location: Chr.14:94619289 on build GRCh38
• Cytoband: 14q32.13

Target Gene Details

• Entrez Gene ID: 12
• Gene Name: serpin family A member 3
• Gene Aliases: AACT, ACT, GIG24, GIG25
• Location: Chr.14:94612377-94624053 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINA3	NM_001085.4	3	817	NP_001076.2
	AB209060.1			BAD92297.1
	AF089747.1	2	692	AAD08810.1
	AK093049.1	6	1701
	AK096120.1	1	1648
	AK123091.1	3	1886
	AY513275.1	3	771	AAT08028.1
	AY513276.1	3	765	AAT08029.1
	BC003559.1	3	790
	BC010530.1	3	787	AAH10530.1
	BC013189.1			AAH13189.1
	BC034554.1	3	781	AAH34554.1
	BC070265.1			AAH70265.1
	J05176.1	2	675	AAA51560.1
	K01500.1	2	749	AAA51543.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470662	Chr.14:94296542 - 94798793 on Build GRCh38	Gain	SERPINA2 SERPINA5 SERPINA13P SERPINA11 SERPINA6 GSC SERPINA1 SERPINA12 SERPINA4 SERPINA9 SERPINA3
nsv565623	Chr.14:94393116 - 94635006 on Build GRCh38	Gain	SERPINA5 SERPINA11 SERPINA12 SERPINA4 SERPINA9 SERPINA3
nsv832865	Chr.14:94499457 - 94667894 on Build GRCh38	Gain	SERPINA5 SERPINA13P SERPINA12 SERPINA4 SERPINA3
esv3635384	Chr.14:94569665 - 94707857 on Build GRCh38	Gain	SERPINA5 SERPINA13P SERPINA4 SERPINA3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

platelet degranulation
acute-phase response
inflammatory response
negative regulation of endopeptidase activity
regulation of lipid metabolic process
maintenance of gastrointestinal epithelium

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
protein binding