Hs00562862_cn

• Gene Symbol: ISLR2
• Assay Reference Genome Location: Chr.15:74131230 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 57611
• Gene Name: immunoglobulin superfamily containing leucine rich repeat 2
• Gene Aliases: LINX
• Location: Chr.15:74128203-74141826 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ISLR2	NM_001130136.1			NP_001123608.1
	NM_001130137.1			NP_001123609.1
	NM_001130138.1			NP_001123610.1
	NM_020851.2			NP_065902.1
	XM_011521840.2			XP_011520142.1
	XM_011521841.1			XP_011520143.1
	XM_017022446.1			XP_016877935.1
	AB040898.2
	AK092297.1
	AK092302.1
	AK290467.1
	AY358316.1			AAQ88682.1
	BC114551.1			AAI14552.1
	BC152429.1
	BI917487.1
	DA791954.1
	DA911394.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833053	Chr.15:74067815 - 74262799 on Build GRCh38	Loss	STRA6 LOC283731 LOC732265 ISLR2 GOLGA6A CCDC33 ISLR
nsv1050884	Chr.15:74102642 - 74197072 on Build GRCh38	Gain	STRA6 LOC283731 ISLR2 ISLR
nsv469619	Chr.15:73999518 - 74173980 on Build GRCh38	Loss	PML LOC283731 LOC732265 ISLR2 GOLGA6A ISLR
nsv827385	Chr.15:74127198 - 74136960 on Build GRCh38	Gain	LOC283731 ISLR2
nsv951993	Chr.15:74124460 - 74137359 on Build GRCh38	Deletion	LOC283731 ISLR2
esv2760040	Chr.15:73922773 - 74172575 on Build GRCh38	Gain+Loss	PML LOC283731 LOXL1-AS1 LOC732265 ISLR2 STOML1 LOXL1 GOLGA6A
nsv1047564	Chr.15:74116495 - 74165840 on Build GRCh38	Gain	LOC283731 ISLR2
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	LOC729739 STRA6 ISLR2 LOC105376731 FAM219B UBL7 ARID3B CYP1A2 C15orf59-AS1 TBC1D21 MIR6882 C15orf39 CPLX3 CYP1A1 COX5A CLK3 NPTN ADPGK C15orf59 LOC283731 LOC732265 SCAMP2 LMAN1L SEMA7A BBS4 HIGD2B REC114 MIR6881 SCAMP5 CSK GOLGA6A PPCDC MPI LOC102723750 ADPGK-AS1 NPTN-IT1 ULK3 CD276 LOC107984728 CYP11A1 UBL7-AS1 EDC3 RPP25 CCDC33 ISLR PML LOXL1-AS1 HCN4 LOC101929333 MIR4513 STOML1 LOXL1 GOLGA6C NEO1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin superfamily cell adhesion molecule

Gene Ontology Categories:

Process(es)

positive regulation of axon extension