Hs00588517_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54146653 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AB014591.1
	AF180474.1			AAF29828.1
	AK160386.1			BAD18729.1
	AK300434.1
	AL133647.1			CAB63766.1
	BC016474.1			AAH16474.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	NDUFA3 LENG1 PRPF31 TMC4 MBOAT7 CNOT3 TFPT
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	OSCAR NDUFA3 LENG1 PRPF31 TMC4 MBOAT7 CNOT3 TFPT TSEN34
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	MIR526A2 MIR515-1 MIR516A2 ZNF765 MIR520H LILRB5 MIR512-2 CACNG6 LILRB2 MIR935 MIR520C MIR518F MIR520B TPM3P9 TFPT MIR518A1 MIR520A LILRA5 MIR519C MIR1323 MIR517B MIR371B PRKCG FAM90A27P TSEN34 MIR518C ZNF665 LILRA6 LILRB3 MIR522 CACNG7 TARM1 ZNF677 MIR518B LOC284379 MIR520F MIR524 ZNF525 PRPF31 MIR525 MIR526B MIR512-1 MBOAT7 ZNF813 ZNF331 MIR517C MIR526A1 NDUFA3 MIR518A2 LENG1 MIR516B2 MIR515-2 CNOT3 MIR518D MIR519A1 MIR519B CACNG8 MIR4752 MIR1283-1 ZNF818P MYADM LOC105372457 MIR521-1 VN1R2 RPS9 ZNF845 MIR516A1 MIR517A MIR523 MIR371A MIR520G VSTM1 MIR527 DPRX ZNF761 MIR1283-2 MIR521-2 MIR519E MIR518E OSCAR MIR519D MIR373 NLRP12 MIR516B1 TMC4 MIR520D MIR498 VN1R4 MIR519A2 BIRC8 MIR372 MIR520E

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding