Hs00638635_cn

• Gene Symbol: DAGLB
• Assay Reference Genome Location: Chr.7:6409534 on build GRCh38
• Cytoband: 7p22.1

Target Gene Details

• Entrez Gene ID: 221955
• Gene Name: diacylglycerol lipase beta
• Gene Aliases: DAGLBETA, KCCR13L
• Location: Chr.7:6409116-6448012 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DAGLB	NM_001142936.1	13	2105	NP_001136408.1
	NM_139179.3	15	2492	NP_631918.3
	AF450090.1	15	2434	AAL47020.1
	AK074210.1	9	1374	BAB85017.1
	AK074584.1	6	1138	BAC11073.1
	AK074744.1	15	2432	BAC11175.1
	AK075128.1	15	2431	BAC11420.1
	AK090943.1	6	1973
	AK091228.1	7	2181
	AK093958.1	12	1829	BAC04258.1
	AK122748.1	12	1858
	AK298910.1	12	1818
	AK298955.1
	BC027603.1	15	2371	AAH27603.1
	CB528359.1	1	427

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1020236	Chr.7:6209299 - 6650746 on Build GRCh38	Gain	DAGLB RAC1 C7orf26 KDELR2 GRID2IP CYTH3 ZNF316 ZNF853 ZDHHC4 FAM220A
nsv606000	Chr.7:6406396 - 6437371 on Build GRCh38	Loss	DAGLB
nsv436904	Chr.7:5035574 - 6713282 on Build GRCh38	Insertion	WIPI2 RBAKDN LOC221946 ACTB RBAK MIR6874 AIMP2 FAM220A DAGLB RAC1 RSPH10B FSCN1 MIR589 SLC29A4 CYTH3 LOC100129484 PMS2 ZNF890P C7orf26 GRID2IP CCZ1 FBXL18 ZNF12 ANKRD61 ZDHHC4 OCM USP42 RNF216-IT1 LOC107986762 KDELR2 RNF216 RBAK-RBAKDN LOC100419773 ZNF316 ZNF853 EIF2AK1 TNRC18 ZNF815P
nsv605999	Chr.7:6357088 - 6433250 on Build GRCh38	Loss	DAGLB RAC1

More Information

Additional Information:

For this assay, SNP(s) [rs73341299] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

lipase

Gene Ontology Categories:

Process(es)

neuroblast proliferation
lipid catabolic process
arachidonic acid metabolic process
neurotransmitter biosynthetic process

Function(s)

metal ion binding
acylglycerol lipase activity