Hs00698988_cn

• Gene Symbol: EIF4A2
• Assay Reference Genome Location: Chr.3:186783593 on build GRCh38
• Cytoband: 3q27.3

Target Gene Details

• Entrez Gene ID: 1974
• Gene Name: eukaryotic translation initiation factor 4A2
• Gene Aliases: BM-010, DDX2B, EIF4A, EIF4F, eIF-4A-II, eIF4A-II
• Location: Chr.3:186783572-186789897 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EIF4A2	NM_001967.3			NP_001958.2
	AF208852.1			AAF64266.1
	AK130087.1
	AK225646.1
	AL117412.1			CAI46218.1
	AL556981.3
	BC012547.1			AAH12547.1
	BC013708.1			AAH13708.1
	BC015842.1			AAH15842.1
	BC048105.1			AAH48105.1
	BT009860.1			AAP88862.1
	D30655.1			BAA06336.1
	S79942.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759206	Chr.3:186619345 - 186849537 on Build GRCh38	Loss	EIF4A2 AHSG ADIPOQ KNG1 SNORD2 MIR1248 HRG RFC4 SNORA81 SNORA63 SNORA4 FETUB LOC102724699
dgv5005n100	Chr.3:186709551 - 186836503 on Build GRCh38	Gain	SNORA81 SNORA63 EIF4A2 KNG1 SNORA4 SNORD2 MIR1248 LOC102724699 RFC4
nsv1012615	Chr.3:186676249 - 186950429 on Build GRCh38	Gain	ST6GAL1 EIF4A2 ADIPOQ KNG1 SNORD2 MIR1248 HRG RFC4 SNORA81 SNORA63 SNORA4 LOC102724699 ADIPOQ-AS1
esv34136	Chr.3:186697095 - 187036942 on Build GRCh38	Loss	SNORA81 ST6GAL1 SNORA63 EIF4A2 ADIPOQ KNG1 SNORA4 SNORD2 MIR1248 LOC102724699 RFC4 ADIPOQ-AS1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA poly(A) tail shortening
translational initiation
regulation of translational initiation
RNA secondary structure unwinding
viral process
negative regulation of RNA-directed RNA polymerase activity

Function(s)

translation initiation factor activity
ATP-dependent RNA helicase activity
helicase activity
protein binding
ATP binding
ATPase activity
poly(A) RNA binding