Hs00753254_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137180869 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	8	1602	NP_037498.1
	AB037827.1	6	778	BAA92644.1
	AF191337.1	8	1529	AAF05751.1
	AK294601.1	8	1557
	BC001579.1	6	794	AAH01579.1
	BC009487.2	4	393	AAH09487.2
	BC032503.1	8	1534	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	CYSRT1 DPP7 MAN1B1-AS1 TMEM210 MIR3621 TPRN GRIN1 SLC34A3 LOC101930307 LRRC26 TMEM203 NDOR1 UAP1L1 SSNA1 RNF208 MAN1B1 ANAPC2 RNF224
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TUBB4B CYSRT1 C9orf173-AS1 FAM166A TPRN NELFB SLC34A3 EXD3 TMEM203 NDOR1 SSNA1 RNF208 ANAPC2 NRARP TOR4A STPG3 RNF224
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	EDF1 PTGDS MIR4292 C9orf173-AS1 C9orf172 FAM166A MIR3621 LCN12 TPRN NELFB NPDC1 MIR4479 LRRC26 RNF208 C8G PHPT1 ANAPC2 NSMF NRARP TOR4A STPG3 TUBB4B SAPCD2 CYSRT1 MAN1B1-AS1 LCNL1 TMEM210 RABL6 CCDC183 ENTPD8 MAMDC4 C9orf142 DPP7 LOC101930307 EXD3 TMEM203 NOXA1 FBXW5 MIR7114 CCDC183-AS1 CLIC3 PNPLA7 GRIN1 SLC34A3 TRAF2 NDOR1 UAP1L1 SSNA1 ABCA2 MAN1B1 FUT7 PRR31 ENTPD2 RNF224 C9orf139
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TUBB4B CYSRT1 C9orf173-AS1 FAM166A TMEM210 MIR3621 TPRN NELFB GRIN1 SLC34A3 EXD3 LRRC26 TMEM203 NDOR1 SSNA1 RNF208 ANAPC2 NRARP TOR4A STPG3 RNF224
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TUBB4B CYSRT1 C9orf173-AS1 FAM166A TMEM210 MIR3621 TPRN NELFB GRIN1 SLC34A3 EXD3 LRRC26 TMEM203 NDOR1 SSNA1 RNF208 ENTPD8 ANAPC2 NRARP TOR4A STPG3 NOXA1 RNF224
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	SAPCD2 DPP7 MAN1B1-AS1 TMEM210 MIR3621 GRIN1 LOC101930307 NPDC1 LRRC26 UAP1L1 SSNA1 MAN1B1 ANAPC2 FUT7 ENTPD2 C9orf139
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	EDF1 TMEM141 PTGDS MIR4292 C9orf173-AS1 C9orf172 FAM166A MIR3621 LCN12 TPRN NELFB NPDC1 MIR4479 MIR126 LRRC26 SNORA17B LOC100128593 RNF208 LCN6 C8G PHPT1 ANAPC2 NRARP TOR4A STPG3 LCN10 TUBB4B SAPCD2 CYSRT1 MAN1B1-AS1 LCNL1 TMEM210 LCN8 RABL6 AGPAT2 MIR6722 CCDC183 HSPC324 MAMDC4 C9orf142 DPP7 EGFL7 LOC101930307 FAM69B LCN15 EXD3 TMEM203 FBXW5 CCDC183-AS1 SNHG7 LINC01451 CLIC3 GRIN1 SLC34A3 SNORA17A TRAF2 NDOR1 UAP1L1 SSNA1 ABCA2 MAN1B1 FUT7 PRR31 ENTPD2 RNF224 C9orf139

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity