Hs00824395_cn

• Gene Symbol: PMEPA1
• Assay Reference Genome Location: Chr.20:57648743 on build GRCh38
• Cytoband: 20q13.31

Target Gene Details

• Entrez Gene ID: 56937
• Gene Name: prostate transmembrane protein, androgen induced 1
• Gene Aliases: STAG1, TMEPAI
• Location: Chr.20:57648392-57711536 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PMEPA1	NM_001255976.1	4	4296	NP_001242905.1
	NM_020182.4	4	4567	NP_064567.2
	NM_199169.2	4	4220	NP_954638.1
	NM_199170.2	4	4213	NP_954639.1
	NM_199171.2	4	4278	NP_954640.1
	AF305616.1	4	4494	AAL16781.1
	AK024618.1	1	1442
	BQ008707.1	1	368

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2758802	Chr.20:57595722 - 58113215 on Build GRCh38	Loss	PMEPA1 MIR4532 LOC100129869 NKILA ZBP1

More Information

Additional Information:

For this assay, SNP(s) [rs112660826,rs201737117] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of SMAD protein complex assembly
negative regulation of transforming growth factor beta receptor signaling pathway
androgen receptor signaling pathway
negative regulation of pathway-restricted SMAD protein phosphorylation

Function(s)

protein binding
WW domain binding
R-SMAD binding