Hs00878793_cn

• Gene Symbol: C14orf169
• Assay Reference Genome Location: Chr.14:73492188 on build GRCh38
• Cytoband: 14q24.3

Target Gene Details

• Entrez Gene ID: 79697
• Gene Name: chromosome 14 open reading frame 169
• Gene Aliases: MAPJD, NO66, ROX, URLC2, hsNO66
• Location: Chr.14:73490934-73493401 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
C14orf169	NM_024644.4	1	1255	NP_078920.2
	AB101204.1	1	1363
	AK025455.1	1	1225	BAB15138.1
	AK299994.1	2	916
	AY390535.1	1	1222	AAR27292.1
	BC011350.1	1	1224	AAH11350.1
	BC071954.1	1	1202	AAH71954.1
	BX390965.1	1	403

Target Gene Details

• Entrez Gene ID: 399671
• Gene Name: HEAT repeat containing 4
• Gene Aliases: -
• Location: Chr.14:73478484-73634418 on Build GRCh38
• Assay Gene Location: Within Intron 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HEATR4	NM_001220484.1			NP_001207413.1
	NM_203309.2			NP_976054.2
	XM_006720143.2			XP_006720206.1
	XM_011536760.2			XP_011535062.1
	XM_017021289.1			XP_016876778.1
	AK093515.1
	AK302564.1
	BC047590.1			AAH47590.1
	GU727638.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3892561	Chr.14:73365865 - 73620531 on Build GRCh38	Gain	NUMB ACOT6 ACOT2 ACOT1 LOC101928143 LOC105370561 C14orf169 ACOT4 HEATR4
nsv1035460	Chr.14:72854572 - 73897173 on Build GRCh38	Gain	ACOT6 PSEN1 RBM25 ACOT4 ZNF410 LOC101928123 LOC100506476 LOC100506498 NUMB ACOT2 DPF3 ACOT1 DNAL1 LOC101928143 ZFYVE1 MIR4505 PNMA1 LOC105370561 PTGR2 ELMSAN1 C14orf169 HEATR4 DCAF4 PAPLN
nsv510643	Chr.14:73483755 - 73582944 on Build GRCh38	Deletion	ACOT2 ACOT1 C14orf169 HEATR4

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase

Gene Ontology Categories:

Process(es)

chromatin remodeling
transcription, DNA-templated
peptidyl-amino acid modification
histone H3-K4 demethylation
ribosome biogenesis
post-translational protein modification
negative regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
oxidation-reduction process
histone H3-K36 demethylation

Function(s)

iron ion binding
protein binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
histone demethylase activity (H3-K4 specific)
histone demethylase activity (H3-K36 specific)